According to a report published in the Wall Street Journal, about one person in 250,000 to 300,000 taking Serzone antidepressant will suffer liver failure.

A number of U.S. psychiatrists became concerned about Serzone antidepressant and the liver failure problem following the Canadian government issued warning on June 20, 2001.

A company spokeswoman at Bristol-Myers was asked why Serzone warnings were sent to Canada but not to American physicians warning of the possible fatal liver damage Serzone antidepressant can cause. The spokeswoman, Tracy Fury, responded that, "We didn't' think it was necessary in the U.S. because what happened in Canada was specific to Canada."

Side Effects of Serzone Antidepressant

  • Skin
    and yellow eyes
  • Bruising
  • Swollen stomach
  • Itching
  • Loss of
    weight and appetite/
  • Pale or black stools/dark urine
  • Tiredness/
    loss of con-centration/ confusion/ personality changes
  • Problems

Serzone Antidepressant

Between 1987 and 1997, the percentage of Americans being treated for depression more than tripled nationwide, from 0.7 percent to 2.3 percent. The introduction of Serzone antidepressant to the U.S. market came with great expectations because the antidepressant drug claimed fewer sexual side effects. There were side effects that Serzone antidepressant patients did not anticipate, though, and a pre-marketing study indicated this when 16% of the patients discontinued the use of the antidepressant because of adverse Serzone side effects. Reports of serious, life-threatening Serzone antidepressant side effects began to surface involving cases of liver failure leading to transplantation and/or death.

Bristol-Myers Squibb Company, the manufacturer of Serzone antidepressant, is now required by the FDA to include a Black Box warning label that advises Serzone patients of the life-threatening liver failure instances that can occur when using the antidepressant drug. Approved in 1994, Serzone antidepressant has been used by approximately 8.3 million people worldwide, 7 million in the U.S. alone. Bristol-Myers has generated about $400 million in annual sales with Serzone antidepressant alone.

If you would like to learn more about your legal rights involving Serzone antidepressant, please contact us.

Bristol-Myers Ordered to Include Strongest FDA Warning For Serzone Label

Bristol-Myers Squibb was told by the FDA on December 7, 2001 to include a Black Box warning on all Serzone antidepressant labels to inform patients of the serious risk of life threatening liver damages that had been surfacing. A Black Box warning is the strongest type of warning that the FDA can require in a drug's labeling. The Serzone antidepressant label change required by the FDA also had to include a warning to aware patients that liver failure can result in death or the need for a liver transplant. Bristol-Myers had to send letters alerting doctors of the potential Serzone liver failure that could occur when administering the antidepressant medication.

Again, on January 9, 2002, the Serzone antidepressant label was revised when the FDA and BMS added a Black Box Warning and strengthened the WARNINGS, CONTRAINDICATIONS, and PRECAUTIONS sections of the label for Serzone antidepressant drug. Rare cases of liver failure leading to transplant and/or death in Serzone antidepressant drug patients have been reported. A new Patient Package Insert is also provided in the product packaging.

If you would like to learn more about your legal rights involving Serzone antidepressant, please contact us.
Serzone Liver Failure

The warning that the FDA ordered be added to the label of Serzone antidepressant included that the time for reported liver failure cases resulting in death or transplant generally ranged from two weeks to six months on Serzone antidepressant therapy. Over 109 cases of serious liver damage have been reported as a result of Serzone antidepressant with at least 23 cases of liver failure that resulted in 16 liver transplants and/or died.
Importance of the Liver

The liver is the largest organ in the body situated on the right hand side of the body behind the lower ribs. It performs many complex functions that are essential to life and health including, making proteins that enable the blood to clot and allow the body to fight infection, converting food into substances that allow repair and growth, producing bile that assists the absorption of fats and certain vitamins, and processing and removing drugs and other toxic substances.

Serzone Antidepressant Lawsuit

Our experienced and proven Serzone lawyers are dedicated to ensuring that every individual that has endured or is still enduring the serious side effects of Serzone antidepressant receive the proper compensation for the injuries suffered. To learn more about your legal rights and Serzone antidepressant, please contact us.

Serzone Black Box Warning

A Black Box warning is the strongest type of warning that the FDA can require in a drug's labeling.
click here to read about the FDA's warning on Serzone antidepressant. . .

:Quick Serzone

Brand name: Serzone

Generic name: nefazodone HCL tablets

How Serzone antidepressant is administered: Serzone antidepressant comes in the form of tablets and are taken orally. They come in five dosages: 50 mg, 100 mg, 150 mg, 200 mg, and 250 mg.

What to do if still taking Serzone antidepressant: If you are still taking Serzone antidepressant drug you are advised to immediately talk to your doctor about the best options to discontinue the use of the drug that has been linked to dangerous cases of Serzone liver damage.

Contact us to learn more about your legal rights concerning Serzone antidepressant.

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